In 2018, global investment in PrEP R&D amounted to US$109 million. This is a 73 percent increase from 2017 and the highest funding recorded in more than a decade. The impetus behind this surge is the 75 percent increase in investment from the public sector, rising from US$38.6 million to US$67.5 million. The US NIH and USAID were the two leading donors at US$36.6 million and US$23.8 million, respectively.
Commercial sector investment in PrEP totaled US$20.2 million; it must be noted, however, that a lack of reporting from the commercial sector explains the absence of investment in past years. Philanthropic investment decreased by 12 percent in 2018, a trend that is linked directly to the decline in BMGF funding from US$24 million to US$21 million.
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